 John Agar as a character Prof. Clete Ferguson | John Agar also starred in the next movies:- "Big Jake" in a role of Bert Ryan;
- "Sands of Iwo Jima" in a role of Pfc. Peter Conway;
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 John Bromfield as a character Joe Hayes | John Bromfield starred only in the movie "Revenge of the Creature" |
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 Nestor Paiva as a character Lucas | Nestor Paiva also starred in the next movies:- "All That Heaven Allows" in a role of Manuel;
- "The Four Horsemen of the Apocalypse" in a role of Miguel;
- "Creature from the Black Lagoon" in a role of Captain Lucas;
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 Grandon Rhodes as a character Jackson Foster | Grandon Rhodes also starred in the next movies:- "Earth vs. the Flying Saucers" in a role of Gen. Edmunds;
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 Dave Willock as a character Lou Gibson | Dave Willock starred only in the movie "Revenge of the Creature" |
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 Robert Williams as a character George Johnson | Robert Williams starred only in the movie "Revenge of the Creature" |
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 Charles Cane as a character Police Captain | Charles Cane starred only in the movie "Revenge of the Creature" |
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 Ricou Browning as a character The Gill Man | Ricou Browning also starred in the next movies:- "Creature from the Black Lagoon" in a role of The Gill Man;
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 Mike Doyle as a character Cop | Mike Doyle also starred in the next movies:- "Laws of Attraction" in a role of Michael Rawson;
- "P.S. I Love You" in a role of Leprechaun;
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 Clint Eastwood as a character Lab Technician | Clint Eastwood also starred in the next movies:- "A Fistful of Dollars" in a role of Joe;
- "Magnum Force" in a role of Insp. 'Dirty' Harry Callahan;
- "In the Line of Fire" in a role of Secret Service Agent Frank Horrigan;
- "For a Few Dollars More" in a role of Monco;
- "Dirty Harry" in a role of Insp. Harry Callahan;
- "The Bridges of Madison County" in a role of Robert Kincaid;
- "Unforgiven" in a role of William 'Bill' Munny;
- "The Rookie" in a role of Nick Pulovski;
- "Two Mules for Sister Sara" in a role of Hogan;
- "Coogan's Bluff" in a role of Deputy Sheriff Walt Coogan;
- "Kelly's Heroes" in a role of Pvt. Kelly;
- "Where Eagles Dare" in a role of Lt. Morris Schaffer;
- "The Good, the Bad and the Ugly" in a role of Blondie;
- "Pale Rider" in a role of Preacher;
- "The Outlaw Josey Wales" in a role of Josey Wales;
- "The Beguiled" in a role of Cpl. John McBurney;
- "High Plains Drifter" in a role of The Stranger;
- "Paint Your Wagon" in a role of Pardner;
- "Tightrope" in a role of Capt. Wes Block;
- "The Dead Pool" in a role of Insp. 'Dirty' Harry Callahan;
- "Sudden Impact" in a role of Harry Callahan;
- "Honkytonk Man" in a role of Red Stovall;
- "Blood Work" in a role of Terry McCaleb;
- "Absolute Power" in a role of Luther Whitney;
- "Gran Torino" in a role of Walt Kowalski;
- "A Perfect World" in a role of Chief Red Garnett;
- "Heartbreak Ridge" in a role of Gunnery Sgt. Tom 'Gunny' Highway;
- "Escape from Alcatraz" in a role of Frank Morris;
- "The Enforcer" in a role of Insp. 'Dirty' Harry Callahan;
- "Thunderbolt and Lightfoot" in a role of John ;
- "Firefox" in a role of Mitchell Gant;
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 Jack Gargan as a character Skipper | Jack Gargan also starred in the next movies:- "20000 Leagues Under the Sea" in a role of Reporter from The Post;
- "The Dark Mirror" in a role of Waiter;
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 Charles Gibb as a character Cop | Charles Gibb starred only in the movie "Revenge of the Creature" |
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 Brett Halsey as a character Pete, teen killed by Gill-Man | Brett Halsey also starred in the next movies:- "To Hell and Back" in a role of Saunders;
- "A Cat In The Brain" in a role of Human Monster;
- "Capers" in a role of Curtis;
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 Don C. Harvey as a character Joe's Searchlight Partner | Don C. Harvey also starred in the next movies:- "Women's Prison" in a role of Chief Guard Tierney;
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 Tom Hennesy as a character The Gill Man (on land)/Marineland Diver | Tom Hennesy starred only in the movie "Revenge of the Creature" |
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