Alyson Court as a character Claire Redfield | Alyson Court also starred in the next movies:- "Care Bears Movie II: A New Generation" in a role of Dawn;
- "Jerry and Tom" in a role of Jacki;
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Paul Mercier as a character Leon S. Kennedy | Paul Mercier starred only in the movie "Resident Evil: Degeneration" |
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Steve Blum as a character Greg Glenn | Steve Blum also starred in the next movies:- "Dante's Inferno: An Animated Epic" in a role of Lucifer;
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Crispin Freeman as a character Frederic Downing | Crispin Freeman starred only in the movie "Resident Evil: Degeneration" |
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Roger Craig Smith as a character Curtis Miller | Roger Craig Smith also starred in the next movies:- "Tinker Bell and the Lost Treasure" in a role of Stone;
- "Disney Princess Enchanted Tales: Follow Your Dreams" in a role of Prince Phillip;
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Michael Sorich as a character Senator Ron Davis | Michael Sorich starred only in the movie "Resident Evil: Degeneration" |
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Laura Bailey as a character Angela Miller | Laura Bailey starred only in the movie "Resident Evil: Degeneration" |
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Michelle Ruff as a character Rani | Michelle Ruff starred only in the movie "Resident Evil: Degeneration" |
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