Matthew Perry as a character Mike O'Donnell - Adult | Matthew Perry also starred in the next movies:- "Serving Sara" in a role of Joe Tyler;
- "The Whole Nine Yards" in a role of Nicholas 'Oz' Oseransky;
- "The Whole Ten Yards" in a role of Oz;
- "Three to Tango" in a role of Oscar Novak;
- "Numb" in a role of Hudson;
- "Birds of America" in a role of Morrie;
- "Almost Heroes" in a role of Leslie Edwards;
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Zac Efron as a character Mike O' Donnell at 17 | Zac Efron also starred in the next movies:- "Hairspray" in a role of Link Larkin;
- "High School Musical 2" in a role of Troy Bolton;
- "High School Musical 3: Senior Year" in a role of Troy Bolton;
- "Me and Orson Welles" in a role of Richard Samuels;
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Leslie Mann as a character Scarlett O'Donnell - Adult | Leslie Mann also starred in the next movies:- "Big Daddy" in a role of Corinne Maloney;
- "Last Man Standing" in a role of Wanda;
- "The Cable Guy" in a role of Robin Harris;
- "Knocked Up" in a role of Debbie;
- "The 40 Year Old Virgin" in a role of Nicky;
- "George of the Jungle" in a role of Ursula Stanhope;
- "Funny People" in a role of Laura;
- "Stealing Harvard" in a role of Elaine Warner;
- "I Love You Phillip Morris" in a role of Debbie;
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Thomas Lennon as a character Ned Freedman | Thomas Lennon also starred in the next movies:- "Memento" in a role of Doctor;
- "The Hitchhiker's Guide to the Galaxy" in a role of Eddie the Computer;
- "Herbie Fully Loaded" in a role of Larry Murphy;
- "Reno 911!: Miami" in a role of Lieutenant Jim Dangle;
- "How to Lose a Guy in 10 Days" in a role of Thayer;
- "Out Cold" in a role of Eric Montclare;
- "Hancock" in a role of Mike;
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Michelle Trachtenberg as a character Maggie O'Donnell | Michelle Trachtenberg also starred in the next movies:- "EuroTrip" in a role of Jenny;
- "Black Christmas" in a role of Melissa Kitt;
- "Ice Princess" in a role of Casey Carlyle;
- "Harriet the Spy" in a role of Harriet M. Welsch;
- "Mysterious Skin" in a role of Wendy;
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Allison Miller as a character Scarlett at 17 | Allison Miller also starred in the next movies:- "Blood: The Last Vampire" in a role of Alice Mckee;
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Tyler Steelman as a character Ned Freedman at 17 | Tyler Steelman starred only in the movie "17 Again" |
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Katerina Graham as a character Jaime | Katerina Graham starred only in the movie "17 Again" |
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Sterling Knight as a character Alex O'Donnell | Sterling Knight starred only in the movie "17 Again" |
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Melora Hardin | Melora Hardin also starred in the next movies:- "The Comebacks" in a role of Barb Fields;
- "Absolute Power" in a role of Christy Sullivan;
- "The Dukes" in a role of Diane;
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Hunter Parrish as a character Stan | Hunter Parrish also starred in the next movies:- "Freedom Writers" in a role of Ben;
- "Down in the Valley" in a role of Kris;
- "RV" in a role of Earl Gornicke;
- "Sleepover" in a role of Lance;
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Melissa Ordway as a character Lauren | Melissa Ordway starred only in the movie "17 Again" |
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Ed Ackerman as a character School Cop | Ed Ackerman also starred in the next movies:- "The Flock" in a role of Louis Kessler;
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Daniel Bateman as a character Dancer | Daniel Bateman starred only in the movie "17 Again" |
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Michael Bretten as a character Teen Boy In Pool | Michael Bretten also starred in the next movies:- "Player 5150" in a role of Dwight's High School Friend;
- "Play the Game" in a role of Trendy Player In Bar;
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