James Stewart as a character Det. John 'Scottie' Ferguson | James Stewart also starred in the next movies:- "Rear Window" in a role of L. B. Jefferies;
- "American Tail: Fievel Goes West, An" in a role of Wylie Burp;
- "Two Rode Together" in a role of Marshal Guthrie McCabe;
- "It's a Wonderful Life" in a role of George Bailey;
- "Bell Book and Candle" in a role of Shepherd 'Shep' Henderson;
- "Mr. Hobbs Takes a Vacation" in a role of Roger Hobbs;
- "Night Passage" in a role of Grant McLaine;
- "Anatomy of a Murder" in a role of Paul Biegler;
- "The Shootist" in a role of Dr. E.W. Hostetler;
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Kim Novak as a character Judy Barton | Kim Novak also starred in the next movies:- "The Man with the Golden Arm" in a role of Molly;
- "Picnic" in a role of Madge Owens;
- "Bell Book and Candle" in a role of Gillian 'Gil' Holroyd;
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Barbara Bel Geddes as a character Marjorie 'Midge' Wood | Barbara Bel Geddes starred only in the movie "Vertigo" |
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Tom Helmore as a character Gavin Elster | Tom Helmore also starred in the next movies:- "Designing Woman" in a role of Zachary Wilde;
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Henry Jones as a character Coroner | Henry Jones also starred in the next movies:- "The Grifters" in a role of Simms;
- "Butch Cassidy and the Sundance Kid" in a role of Bike Salesman;
- "Rascal" in a role of Garth Shadwick;
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Raymond Bailey as a character Scottie's doctor | Raymond Bailey also starred in the next movies:- "Sabrina" in a role of Member of the Board;
- "Herbie Rides Again" in a role of Lawyer;
- "Picnic" in a role of Mr. Benson;
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Ellen Corby as a character Manager of McKittrick Hotel | Ellen Corby also starred in the next movies:- "Sabrina" in a role of Miss McCardle;
- "Shane" in a role of Mrs. Liz Torrey;
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Konstantin Shayne as a character Pop Leibel | Konstantin Shayne starred only in the movie "Vertigo" |
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Lee Patrick as a character Car owner mistaken for Madeleine | Lee Patrick also starred in the next movies:- "Auntie Mame" in a role of Doris Upson;
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Jack Ano as a character Bit part | Jack Ano starred only in the movie "Vertigo" |
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John Benson as a character Salesman | John Benson also starred in the next movies:- "The Rainmaker" in a role of Townsman;
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Paul Bryar as a character Det. Capt. Hansen | Paul Bryar starred only in the movie "Vertigo" |
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Bruno Della Santina as a character Waiter at Ernie's | Bruno Della Santina starred only in the movie "Vertigo" |
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Carlo Dotto as a character Ernie's bartender | Carlo Dotto starred only in the movie "Vertigo" |
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