 Willem Dafoe as a character Paul Smecker | Willem Dafoe also starred in the next movies:- "Platoon" in a role of Sgt. Elias Grodin;
- "Once Upon a Time in Mexico" in a role of Barillo;
- "Spider-Man" in a role of Green Goblin/Norman Osborn;
- "New Rose Hotel" in a role of X;
- "Auto Focus" in a role of John Carpenter;
- "The English Patient" in a role of David Caravaggio;
- "xXx: State of the Union" in a role of Gen. George Octavius Deckert;
- "To Live and Die in L.A." in a role of Eric 'Rick' Masters;
- "The Life Aquatic with Steve Zissou" in a role of Klaus Daimler;
- "Finding Nemo" in a role of Gill;
- "Wild at Heart" in a role of Bobby Peru;
- "Clear and Present Danger" in a role of John Clark;
- "Speed 2: Cruise Control" in a role of John Geiger;
- "Spider-Man 2" in a role of Green Goblin/Norman Osborn;
- "Manderlay" in a role of Grace's Father;
- "American Psycho" in a role of Det. Donald Kimball;
- "Mr. Bean's Holiday" in a role of Carson Clay;
- "The Walker" in a role of Senator Larry Lockner;
- "The Clearing" in a role of Arnold Mack;
- "Adam Resurrected" in a role of Commandant Klein;
- "Antichrist" in a role of He;
- "White Sands" in a role of Deputy Sheriff Ray Dolezal;
- "Overnight" in a role of Himself;
- "Off Limits" in a role of Buck McGriff;
- "Fantastic Mr. Fox" in a role of Rat;
- "Shadow of the Vampire" in a role of Max Schreck;
- "Daybreakers" in a role of Elvis;
- "Mississippi Burning" in a role of Agent Alan Ward;
- "The Last Temptation of Christ" in a role of Jesus;
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 Sean Patrick Flanery as a character Connor MacManus | Sean Patrick Flanery also starred in the next movies:- "Demon Hunter" in a role of Jake Greyman;
- "Simply Irresistible" in a role of Tom Bartlett;
- "The Gunman" in a role of Ben Simms;
- "Veritas, Prince of Truth" in a role of Veritas;
- "Powder" in a role of Jeremy 'Powder' Reed;
- "The Boondock Saints II: All Saints Day" in a role of Connor MacManus;
- "Deadly Impact" in a role of Tom Armstrong;
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 Norman Reedus as a character Murphy MacManus | Norman Reedus also starred in the next movies:- "Blade II" in a role of Scud;
- "Gossip" in a role of Travis;
- "Pulse (aka Octane)" in a role of Recovery Man;
- "Hero Wanted" in a role of Swain;
- "Moscow Chill" in a role of Ray Perso;
- "Pandorum" in a role of Shepard;
- "Messengers 2: The Scarecrow" in a role of John Rollins;
- "Deuces Wild" in a role of Marco;
- "The Boondock Saints II: All Saints Day" in a role of Murphy MacManus;
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 David Della Rocco as a character David Della 'Roc/Funny Man' Rocco | David Della Rocco also starred in the next movies:- "The Boondock Saints II: All Saints Day" in a role of Rocco;
- "Jake's Corner" in a role of Wheels;
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 Billy Connolly as a character Il Duce | Billy Connolly also starred in the next movies:- "The Last Samurai" in a role of Zebulon Gant;
- "White Oleander" in a role of Barry Kolker;
- "Timeline" in a role of Prof. E.A. Johnston;
- "Lemony Snicket's A Series of Unfortunate Events" in a role of Uncle Monty;
- "Garfield: A Tail of Two Kitties" in a role of Lord Dargis;
- "Fido" in a role of Fido;
- "Open Season" in a role of McSquizzy;
- "The X-Files: I Want to Believe";
- "Indecent Proposal" in a role of Auction M.C.;
- "Water" in a role of Delgado Fitzhugh;
- "Overnight" in a role of Himself;
- "Beautiful Joe" in a role of Joe;
- "The Boondock Saints II: All Saints Day" in a role of Poppa M;
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 David Ferry as a character Detective Dolly | David Ferry also starred in the next movies:- "Control Factor" in a role of Detective Jordan;
- "Darkman II: The Return of Durant" in a role of Eddie;
- "Back in Action" in a role of Head Lawyer;
- "The Boondock Saints II: All Saints Day" in a role of Detective Dolly;
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 Brian Mahoney as a character Detective Duffy | Brian Mahoney also starred in the next movies:- "The Boondock Saints II: All Saints Day" in a role of Detective Duffy;
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 Bob Marley as a character Detective Greenly | Bob Marley also starred in the next movies:- "The Boondock Saints II: All Saints Day" in a role of Detective Greenly;
- "Classic Albums: Bob Marley & the Wailers - Catch a Fire" in a role of Himself;
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 Richard Fitzpatrick as a character The Chief | Richard Fitzpatrick also starred in the next movies:- "Confessions of a Teenage Drama Queen" in a role of Mr. Gerard;
- "Time Bomb" in a role of Burgess;
- "The River King" in a role of Police Chief;
- "The Boondock Saints II: All Saints Day" in a role of The Chief;
- "Survival of the Dead" in a role of Seamus Muldoon;
- "Bitten" in a role of Roger;
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 William Young as a character Monsignor | William Young starred only in the movie "The Boondock Saints" |
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 Robert Pemberton as a character Macklepenny | Robert Pemberton starred only in the movie "The Boondock Saints" |
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 Bill Craig as a character McGerkin | Bill Craig starred only in the movie "The Boondock Saints" |
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 Dot Jones as a character Rosengurtle Baumgartener | Dot Jones starred only in the movie "The Boondock Saints" |
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 Scott Griffith as a character Ivan Checkov | Scott Griffith starred only in the movie "The Boondock Saints" |
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 Layton Morrison as a character Vladdy | Layton Morrison starred only in the movie "The Boondock Saints" |
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